Description

Buy Vasoactive Intestinal Peptide (VIP) 5mg Online UK

For laboratories and research institutions investigating neuropeptide signalling, VPAC receptor pharmacology, and immunomodulatory pathways, our Vasoactive Intestinal Peptide (VIP) 5mg delivers verified ≥98% HPLC purity with full mass spectrometry confirmation. This 28-amino-acid neuropeptide—a member of the secretin/glucagon superfamily—is widely distributed in the central and peripheral nervous systems and functions as a neuroendocrine hormone and putative neurotransmitter. Manufactured under stringent controlled conditions, vacuum-sealed in lyophilised form, and preserved through our temperature-monitored cold-chain, every batch is accompanied by a comprehensive Certificate of Analysis. With 100% domestic UK stockholding and same-day dispatch on orders placed before 2:00 PM GMT, we eliminate customs delays and temperature excursions that compromise research integrity.

Research Applications & Key Benefits

• VPAC Receptor Binding & Signalling Studies: VIP is a potent agonist at VPAC1 and VPAC2 receptors (also known as VIP/pituitary adenylate cyclase-activating polypeptide receptors), with high-affinity binding demonstrated in multiple cell lines (KD = 1.6–1.7 nM). Research applications include receptor binding kinetics, adenylate cyclase activation, and downstream cAMP signalling pathway investigations.

• Immunomodulatory Pathway Research: VIP modulates the activity of numerous immune system cell types and blocks mitogen-activated proliferation of T cells by preventing interleukin-2 production. It has been investigated in lymphocyte-based studies examining immune regulation, inflammation modulation, and cytokine signalling pathways.

• Neuroprotective & Neurotransmitter Studies: VIP stimulates neuronal survival and provides protection against oxidant injury. Research has examined its neuroprotective actions mediated by the release of activity-dependent neurotrophic factors from glial cells, as well as its modulation of cholinergic and serotonergic neurotransmitter systems.

• VPAC Receptor Selectivity Studies: VIP serves as a reference compound for developing simplified, metabolically stable analogs with VPAC1 selectivity or dual VPAC1/VPAC2 affinity. The peptide’s receptor pharmacology makes it valuable for structure-activity relationship studies and receptor imaging research.

• Gastrointestinal & Epithelial Cell Research: As a neuropeptide expressed in airway epithelial cells, secretory glands, and the gastrointestinal tract, VIP is utilised in research examining electrolyte secretion, glycogen metabolism, and epithelial barrier function.

• Fragment & Metabolite Studies: VIP fragments such as VIP4–28 and VIP6–28 have been investigated for their distinct receptor activity profiles—including VPAC1 agonism and VPAC2 antagonism—supporting research into receptor subtype-specific signalling and peptide metabolism.

The Pure Peptides UK Advantage

100% Domestic UK Stockholding
All inventory is warehoused within the United Kingdom, eliminating international shipping delays, customs clearance uncertainties, and extended transit times. Your order ships from our UK facility directly to your laboratory.

Same-Day Dispatch Commitment
Orders confirmed before 2:00 PM GMT are dispatched the same working day via tracked courier services, ensuring minimal time between order placement and receipt.

Batch-Specific Certificates of Analysis
Each vial is traceable to its production batch, with full HPLC chromatograms, mass spectrometry data, and purity verification documentation available. Independent third-party testing (≥98% purity typical) confirms identity and standards.

Cold-Chain Integrity
Temperature-controlled storage at 2°C–8°C prior to dispatch, with insulated packaging designed to maintain lyophilised product stability during transit. Long-term storage recommended at -20°C for extended stability. Avoid repeated freeze/thaw cycles after reconstitution.

Discreet & Secure Delivery
Plain, unbranded outer packaging protects your research privacy. All shipments are fully tracked with delivery confirmation. No compound names appear on external packaging.

Dedicated UK Support
Our UK-based technical support team is available to assist with product queries, storage guidance, and reconstitution protocols. No dosing, administration, or clinical guidance is provided—we support your research objectives exclusively.

Regulatory Compliance & In-Vitro Disclaimer

FOR IN-VITRO RESEARCH & LABORATORY USE ONLY

This product is a research-grade chemical supplied exclusively for:

• In-vitro laboratory experimentation

• Analytical testing and method development

• Biochemical assay and cellular model research

• Scientific study and educational purposes 

STRICTLY NOT FOR:

• Human consumption, administration, or therapeutic application

• Veterinary use or animal experimentation outside licensed laboratory settings

• Diagnostic, treatment, or preventative medical purposes

• Any application outside a controlled laboratory environment 

All users must comply with applicable UK and EU regulations governing the procurement, handling, and use of research chemicals. This product is not a medicinal product, dietary supplement, or foodstuff. No medical or therapeutic claims are made, expressed, or implied. Researchers are responsible for ensuring that their intended use complies with institutional ethics committees and relevant regulatory frameworks.