Description

Buy KPV – 5mg Online UK 

For laboratories and research institutions investigating melanocortin-related signalling, inflammatory pathway modulation, and peptide-mediated immune responses, our KPV 5mg delivers verified ≥98% HPLC purity with comprehensive analytical testing. This synthetic tripeptide—Lys-Pro-Val (KPV)—corresponds to the C-terminal fragment of α-melanocyte-stimulating hormone (α-MSH 11–13) and represents the minimal bioactive sequence responsible for the anti-inflammatory properties of the parent hormone, without melanotropic effects. Manufactured under stringent controlled conditions, vacuum-sealed in lyophilised form, and preserved through our temperature-monitored cold-chain, every batch is accompanied by a comprehensive Certificate of Analysis. With 100% domestic UK stockholding and same-day dispatch on orders placed before 2:00 PM GMT, we eliminate customs delays that compromise research integrity.

Research Applications & Key Benefits

• Melanocortin Signalling Pathway Research: KPV is a molecular probe for studying melanocortin-associated signalling independently of full-length α-MSH. Research applications include receptor-binding studies, investigation of melanocortin receptor (MC-R) involvement—notably MC1R and MC3R—and examination of downstream intracellular signalling mechanisms associated with immune modulation and inflammatory responses.

• Inflammatory Pathway Investigations (NF-κB): Research indicates KPV may modulate the NF-κB pathway, acting to regulate inflammatory signalling. Studies investigate its potential to inhibit p65/RelA nuclear import and modulate pro-inflammatory cytokine expression (including IL-6, TNF-α, and IL-1β), making it a key tool for understanding peptide-mediated regulation of inflammatory responses.

• Gastrointestinal & Mucosal Barrier Research: KPV has been studied for its interaction with the PepT1 transporter and its effects on intestinal lining integrity. In research models of colitis, KPV has been investigated for its potential to reduce intestinal inflammation and repair mucosal injury. Its oral stability makes it particularly valuable for gastrointestinal research applications.

• Antimicrobial Activity Studies: In vitro studies have demonstrated activity against specific bacteria and fungi, including Staphylococcus aureus and Candida albicans. Research examines KPV’s role in host defence against pathogens and its potential as a reference compound in antimicrobial peptide studies.

• Dermatological & Skin Research: KPV has been investigated for its effects on inflammatory skin conditions, wound healing, and epithelial repair processes. Unlike α-MSH, KPV is free from melanotropic effects and does not cause pigmentation, making it a focused tool for studying anti-inflammatory mechanisms in skin biology.

• Structure–Activity & Peptide Transport Studies: As a compact tripeptide, KPV serves as a reference compound for structure–activity relationship studies, peptide transport research, and investigations of short peptide signalling profiles distinct from parent hormones.

The Pure Peptides UK Advantage

100% Domestic UK Stockholding
All inventory is warehoused within the United Kingdom, eliminating international shipping delays, customs clearance uncertainties, and extended transit times. Your order ships from our UK facility directly to your laboratory.

Same-Day Dispatch Commitment
Orders confirmed before 2:00 PM GMT are dispatched the same working day via tracked courier services, ensuring minimal time between order placement and receipt.

Batch-Specific Certificates of Analysis
Each vial is traceable to its production batch, with full HPLC chromatograms and purity verification documentation available. Independent UKAS & ISO 9001-accredited laboratory testing confirms identity and purity standards.

Cold-Chain Integrity
Temperature-controlled storage at -20°C prior to dispatch, with temperature-shielded packaging designed to maintain lyophilised product stability during transit. Long-term storage recommended at -20°C in desiccated, dark conditions.

Discreet & Secure Delivery
Plain, unbranded outer packaging protects your research privacy. All shipments are fully tracked with delivery confirmation.

Dedicated UK Support
Our UK-based technical support team is available to assist with product queries, storage guidance, and reconstitution protocols. No dosing, administration, or clinical guidance is provided—we support your research objectives exclusively.

Regulatory Compliance & In-Vitro Disclaimer

FOR IN-VITRO RESEARCH & LABORATORY USE ONLY

This product is a research-grade chemical supplied exclusively for:

• In-vitro laboratory experimentation

• Analytical testing and method development

• Biochemical assay and cellular model research

• Scientific study and educational purposes

STRICTLY NOT FOR:

• Human consumption, administration, or therapeutic application

• Veterinary use or animal experimentation outside licensed laboratory settings

• Diagnostic, treatment, or preventative medical purposes

• Any application outside a controlled laboratory environment

All users must comply with applicable UK and EU regulations governing the procurement, handling, and use of research chemicals. This product is not a medicinal product, dietary supplement, or foodstuff. No medical or therapeutic claims are made, expressed, or implied. Researchers are responsible for ensuring that their intended use complies with institutional ethics committees and relevant regulatory frameworks.