Retatrutide 10mg

£75.00

Product Overview
Product Specifications
Technical Parameter Specification
Product Name Retatrutide 10mg (LY3437943 / Triple GIP/GLP-1/Glucagon Receptor Agonist)
Molecular Sequence Tyr-{Aib}-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-{α-Me-Leu}-Leu-Asp-Lys-{diacid-C20-gamma-Glu-(AEEA)-Lys}-Ala-Gln-{Aib}-Ala-Phe-Ile-Glu-Tyr-Leu-Leu-Glu-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH₂
Molecular Formula C₂₂₁H₃₄₂N₄₆O₆₈
Molecular Weight 4,731.33 – 4,731.34 g/mol
CAS Registry Number 2381089-83-2
Purity Standard ≥98.0% (Verified via HPLC & Mass Spectrometry)
Physical Form Lyophilised Powder (Vacuum-Sealed Glass Vial)
Receptor Activity GCGR: EC₅₀ = 5.79 nM;
GIPR: EC₅₀ = 0.0643 nM;
GLP-1R: EC₅₀ = 0.775 nM
Recommended Storage 2°C – 8°C (Short Term) / -20°C (Long Term)
Solubility H₂O: 33.33 mg/mL (7.04 mM; ultrasonic and adjust pH to 7 with NaOH)
Domestic Fulfillment 100% UK Warehouse Inventory
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Description

Buy Retatrutide – 10mg Online UK 

For laboratories and research institutions investigating multi-receptor signalling, metabolic pathway modulation, and incretin biology, our Retatrutide 10mg delivers verified ≥98% HPLC purity with comprehensive analytical testing. This synthetic 39-amino-acid peptide—also known as LY3437943—exhibits triple agonist activity at the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R), with EC₅₀ values of 5.79, 0.0643, and 0.775nM respectively . Manufactured under stringent controlled conditions, vacuum-sealed in lyophilised form, and preserved through our temperature-monitored cold-chain, every batch is accompanied by a comprehensive Certificate of Analysis. With 100% domestic UK stockholding and same-day dispatch on orders placed before 2:00 PM GMT, we eliminate customs delays that compromise research integrity.

Research Applications & Key Benefits

  • Triple Receptor Pharmacology Studies: Retatrutide functions as a multi-receptor agonist targeting GCGR, GIPR, and GLP-1R . This unique triple agonist profile makes it a valuable molecular probe for investigating receptor binding kinetics, downstream signalling cascades, and the interplay between these three metabolically significant receptor systems in in-vitro models.

  • Metabolic Pathway & Energy Homeostasis Research: The glucagon receptor component of retatrutide promotes hepatic fat mobilisation and increases energy expenditure , while GIP and GLP-1 receptor activation influences insulin secretion and satiety signalling. Research applications include studying integrated metabolic pathway regulation and energy homeostasis mechanisms.

  • Incretin Biology & Receptor Crosstalk Studies: As a single molecule targeting three distinct receptors, retatrutide serves as a tool for investigating receptor crosstalk, biased agonism, and the synergistic effects of concurrent receptor activation in cellular models.

  • Adipose Tissue & Hepatic Lipid Metabolism: The glucagon receptor component makes retatrutide particularly relevant for research examining hepatic lipid metabolism, fatty acid oxidation, and adipose tissue biology. Studies have investigated its effects on liver fat reduction in preclinical models.

  • Structure–Activity Relationship Studies: With its 39-amino-acid sequence incorporating non-natural amino acids including Aib (α-aminoisobutyric acid) and α-Me-Leu, retatrutide provides a model for peptide engineering and stability studies.

Important Regulatory & Safety Information

Clinical Development Status: Retatrutide is currently in Phase 3 clinical development and has not received Marketing Authorisation in the UK, EU, or US for any indication. It remains an investigational compound not approved for therapeutic use.

Legitimate Supply Context: Eli Lilly has not licensed retatrutide to any third-party manufacturer; the product is not available commercially for therapeutic purposes anywhere in the world. Unregulated “research-grade” products sold online carry potential risks including unknown purity, incorrect concentration, and batch variability.

For Accredited Research Institutions Only: This product is supplied exclusively for legitimate in-vitro research purposes to accredited institutions, university laboratories, and research scientists with appropriate ethical approval.

The Pure Peptides UK Advantage

100% Domestic UK Stockholding
All inventory is warehoused within the United Kingdom, eliminating international shipping delays, customs clearance uncertainties, and extended transit times. Your order ships from our UK facility directly to your laboratory.

Same-Day Dispatch Commitment
Orders confirmed before 2:00 PM GMT are dispatched the same working day via tracked courier services, ensuring minimal time between order placement and receipt.

Batch-Specific Certificates of Analysis
Each vial is traceable to its production batch, with full HPLC chromatograms, mass spectrometry data, and purity verification documentation available.

Cold-Chain Integrity
Temperature-controlled storage at 2°C–8°C prior to dispatch, with insulated packaging designed to maintain lyophilised product stability during transit. Long-term storage recommended at -20°C.

Discreet & Secure Delivery
Plain, unbranded outer packaging protects your research privacy. All shipments are fully tracked with delivery confirmation.

Dedicated UK Support
Our UK-based technical support team is available to assist with product queries, storage guidance, and reconstitution protocols. No dosing, administration, or clinical guidance is provided—we support your research objectives exclusively.

Regulatory Compliance & In-Vitro Disclaimer

FOR IN-VITRO RESEARCH & LABORATORY USE ONLY

This product is a research-grade chemical supplied exclusively for:

  • In-vitro laboratory experimentation

  • Analytical testing and method development

  • Biochemical assay and cellular model research

  • Scientific study and educational purposes

STRICTLY NOT FOR:

  • Human consumption, administration, or therapeutic application

  • Veterinary use or animal experimentation outside licensed laboratory settings

  • Diagnostic, treatment, or preventative medical purposes

  • Any application outside a controlled laboratory environment

All users must comply with applicable UK and EU regulations governing the procurement, handling, and use of research chemicals. This product is not a medicinal product, dietary supplement, or foodstuff. No medical or therapeutic claims are made, expressed, or implied. Researchers are responsible for ensuring that their intended use complies with institutional ethics committees and relevant regulatory frameworks.

Additional information

Cap Colour

Purple