Description

Buy MOTS-c 10mg Online UK 

For laboratories and research institutions investigating mitochondrial biology, metabolic pathway signaling, and cellular energy regulation, our MOTS-c 10mg delivers verified ≥98% HPLC purity with comprehensive analytical testing. This 16-amino-acid peptide — encoded within the mitochondrial 12S rRNA region rather than nuclear DNA — represents a distinct class of mitochondrial-derived peptides (MDPs) that function as endocrine signaling molecules. Manufactured under stringent controlled conditions, vacuum-sealed in lyophilised form, and preserved through our temperature-monitored cold-chain, every batch is accompanied by a comprehensive Certificate of Analysis. With 100% domestic UK stockholding and same-day dispatch on orders placed before 2:00 PM GMT, we eliminate customs delays and temperature excursions that compromise research integrity.

Research Applications & Key Benefits

• Mitochondrial-Nuclear Communication Research: MOTS-c is a mitochondrial-derived peptide encoded by a short open reading frame within the mitochondrial 12S ribosomal RNA gene. It is studied as a signaling molecule that mediates communication between mitochondria and the nucleus under conditions of cellular metabolic stress. Unlike nuclear-encoded peptides, MOTS-c provides a unique tool for investigating retrograde mitochondrial signaling pathways.

• AMPK Pathway Activation Studies: Research has demonstrated that MOTS-c activates the AMPK (AMP-activated protein kinase) pathway, a central regulator of cellular energy homeostasis. Laboratory studies utilise MOTS-c to investigate AMPK-mediated metabolic adaptation, glucose uptake mechanisms, and energy-sensing pathways in skeletal muscle cell models.

• Glucose Metabolism & Insulin Sensitivity Research: Preclinical studies have examined MOTS-c’s effects on insulin sensitivity, glucose tolerance, and lipid profiles, with observations of improved glucose metabolism in experimental models. The compound is frequently incorporated into research examining metabolic homeostasis and nutrient sensing mechanisms.

• Cellular Stress Response Investigations: MOTS-c has been studied in the context of cellular adaptation to metabolic stress, with research examining its effects on mitochondrial stress response mechanisms and adaptive nuclear gene expression. This makes it valuable for research into cellular resilience and metabolic adaptation.

• Age-Associated Mitochondrial Biology: Published literature has observed that MOTS-c expression varies across age groups in rodent models, supporting research into age-related mitochondrial decline and metabolic regulation. It is also investigated in longevity research contexts.

• In-Vitro Cell Culture & Biochemical Assays: Suitable for controlled laboratory environments including cell culture supplementation, enzymatic assays, and mitochondrial function studies requiring high-purity mitochondrial-derived peptide.

The Pure Peptides UK Advantage

100% Domestic UK Stockholding
All inventory is warehoused within the United Kingdom, eliminating international shipping delays, customs clearance uncertainties, and extended transit times. Your order ships from our UK facility directly to your laboratory.

Same-Day Dispatch Commitment
Orders confirmed before 2:00 PM GMT are dispatched the same working day via tracked courier services, ensuring minimal time between order placement and receipt.

Batch-Specific Certificates of Analysis
Each vial is traceable to its production batch, with full HPLC chromatograms, mass spectrometry data, and purity verification documentation available. Independent third-party testing confirms identity, purity, and compound integrity.

Cold-Chain Integrity
Temperature-controlled storage at 2°C–8°C prior to dispatch, with insulated packaging designed to maintain lyophilised product stability during transit. Long-term storage recommended at -20°C for extended stability.

Discreet & Secure Delivery
Plain, unbranded outer packaging protects your research privacy. All shipments are fully tracked with delivery confirmation.

Dedicated UK Support
Our UK-based technical support team is available to assist with product queries, storage guidance, and reconstitution protocols. No dosing, administration, or clinical guidance is provided — we support your research objectives exclusively.

Regulatory Compliance & In-Vitro Disclaimer

FOR IN-VITRO RESEARCH & LABORATORY USE ONLY

This product is a research-grade chemical supplied exclusively for:

• In-vitro laboratory experimentation 

• Analytical testing and method development

• Biochemical assay and cellular model research

• Scientific study and educational purposes

STRICTLY NOT FOR:

• Human consumption, administration, or therapeutic application 

• Veterinary use or animal experimentation outside licensed laboratory settings

• Diagnostic, treatment, or preventative medical purposes 

• Any application outside a controlled laboratory environment

All users must comply with applicable UK and EU regulations governing the procurement, handling, and use of research chemicals. This product is not a medicinal product, dietary supplement, or foodstuff. No medical or therapeutic claims are made, expressed, or implied. Researchers are responsible for ensuring that their intended use complies with institutional ethics committees and relevant regulatory frameworks.