Description

Buy Fragment 176-191 5mg UK

For laboratories and research institutions investigating lipid metabolism, adipose tissue biology, and growth hormone fragment-specific signaling, our Fragment 176-191 5mg delivers verified ≥98% HPLC purity with full mass spectrometry confirmation. This synthetic 16-amino-acid peptide corresponds to the C-terminal region of human growth hormone (residues 176–191) and is recognized for its targeted lipolytic activity without the broader systemic effects associated with full-length GH. Manufactured under stringent controlled conditions, vacuum-sealed in lyophilized form, and preserved through our temperature-monitored cold-chain, every batch is accompanied by a comprehensive Certificate of Analysis. With 100% domestic UK stockholding and same-day dispatch on orders placed before 2:00 PM GMT, we eliminate customs delays and temperature excursions that compromise research integrity.

Research Applications & Key Benefits

• Lipid Metabolism & Adipose Tissue Research: Fragment 176-191 is the C-terminal 16-amino-acid segment of human growth hormone, isolated specifically for its fat-metabolising properties. It stimulates lipolysis (fat breakdown) and inhibits lipogenesis (fat formation) in adipose tissue models without the growth-promoting, IGF-1-elevating, or diabetogenic effects of full-length GH.

• Receptor-Independent Signalling Studies: Unlike full-length growth hormone, Fragment 176-191 does not bind the GH receptor in the same manner and does not elevate IGF-1 or affect glucose homeostasis, making it a valuable molecular tool for studying domain-specific, receptor-independent signalling pathways.

• Mitochondrial Energy Regulation: Laboratory studies investigate the peptide’s effects on mitochondrial activity, energy metabolism, and intracellular signalling cascades triggered by HGH fragment-specific sequences.

• Comparative Lipolytic Peptide Research: Frequently studied alongside AOD-9604 (a modified version with an additional N-terminal tyrosine residue) to examine structure-function relationships and lipolytic mechanisms in cellular models.

• Preclinical Metabolic Modelling: Used in in vitro and preclinical studies to model metabolic responses, examine adipocyte biology, and investigate HGH fragment-specific effects on fat metabolism pathways.

The Pure Peptides UK Advantage

100% Domestic UK Stockholding
All inventory is warehoused within the United Kingdom, eliminating international shipping delays, customs clearance uncertainties, and extended transit times. Your order ships from our UK facility directly to your laboratory.

Same-Day Dispatch Commitment
Orders confirmed before 2:00 PM GMT are dispatched the same working day via tracked courier services, ensuring minimal time between order placement and receipt.

Batch-Specific Certificates of Analysis
Each vial is traceable to its production batch, with full HPLC chromatograms, mass spectrometry data, and purity verification documentation available. Independent ISO 17025-accredited laboratory testing confirms identity and purity.

Cold-Chain Integrity
Temperature-controlled storage at 2°C–8°C prior to dispatch, with insulated packaging designed to maintain lyophilised product stability during transit. Long-term storage recommended at -20°C for extended stability.

Discreet & Secure Delivery
Plain, unbranded outer packaging protects your research privacy. All shipments are fully tracked with delivery confirmation. No compound names appear on external packaging.

Dedicated UK Support
Our UK-based technical support team is available to assist with product queries, storage guidance, and reconstitution protocols. No dosing, administration, or clinical guidance is provided—we support your research objectives exclusively.

Regulatory Compliance & In-Vitro Disclaimer

FOR IN-VITRO RESEARCH & LABORATORY USE ONLY

This product is a research-grade chemical supplied exclusively for:

• In-vitro laboratory experimentation

• Analytical testing and method development

• Biochemical assay and cellular model research

• Scientific study and educational purposes

STRICTLY NOT FOR:

• Human consumption, administration, or therapeutic application

• Veterinary use or animal experimentation outside licensed laboratory settings

• Diagnostic, treatment, or preventative medical purposes

• Any application outside a controlled laboratory environment

All users must comply with applicable UK and EU regulations governing the procurement, handling, and use of research chemicals. This product is not a medicinal product, dietary supplement, or foodstuff. No medical or therapeutic claims are made, expressed, or implied. Researchers are responsible for ensuring that their intended use complies with institutional ethics committees and relevant regulatory frameworks .