PT-141 (Bremelanotide) 10mg

Description

Buy PT-141 10 mg (Bremelanotide) Online UK

For laboratories and research institutions conducting neuroscientific and GPCR signalling investigations, our PT-141 (Bremelanotide) 10mg delivers verified ≥98% HPLC purity with full mass spectrometry confirmation. This synthetic cyclic heptapeptide is a potent analogue of alpha-melanocyte-stimulating hormone (α-MSH) that acts as a melanocortin receptor agonist with particular affinity for MC3R and MC4R subtypes . Manufactured under stringent controlled conditions and vacuum-sealed in lyophilised form, every batch is preserved through our temperature-monitored cold-chain. With 100% domestic UK stockholding and same-day dispatch on orders placed before 2:00 PM GMT, we eliminate customs delays and temperature excursions that compromise research integrity. Every batch is accompanied by a comprehensive Certificate of Analysis, ensuring complete experimental traceability for peer-reviewed publication and institutional audit compliance.

Research Applications & Key Benefits

• Melanocortin Receptor Signalling Studies: PT-141 acts as a potent agonist at melanocortin receptors (MC1R, MC3R, MC4R), initiating intracellular signalling cascades associated with cAMP production and downstream transcriptional regulation . It is widely employed as a molecular probe for studying GPCR-mediated signalling pathways and receptor binding kinetics.

• Hypothalamic & Neuroendocrine Research: The compound interacts with melanocortin receptors in the medial preoptic area and paraventricular nucleus of the hypothalamus, making it a valuable reagent for investigating central nervous system melanocortin activity, hypothalamic signalling pathways, and autonomic nervous system modulation .

• Neuropeptide Biology & CNS Studies: As an α-MSH analogue, PT-141 is researched in the context of neuropeptide biology, examining melanocortin pathway signalling in preclinical models of central nervous system function and homeostatic regulation .

• Oncology Research: Recent peer-reviewed studies have investigated bremelanotide’s effects on glioblastoma cell lines, demonstrating that melanocortin receptor activation may suppress survivin expression and induce cell death, identifying MC3R and MC4R as potential therapeutic targets in cancer research .

• Receptor Selectivity & Comparative Studies: Unlike its parent compound Melanotan II, PT-141 exhibits distinct receptor selectivity and signalling characteristics, making it an essential tool for comparative studies of melanocortin receptor pharmacology and signalling bias.

• Structural Stability: The cyclic heptapeptide structure confers enhanced stability while maintaining full melanocortin receptor bioactivity, confirmed through cell-based assays demonstrating potent receptor activation and cAMP accumulation.

The Pure Peptides UK Advantage

100% Domestic UK Stockholding
All inventory is warehoused within the United Kingdom, eliminating international shipping delays, customs clearance uncertainties, and extended transit times. Your order ships from our UK facility directly to your laboratory.

Same-Day Dispatch Commitment
Orders confirmed before 2:00 PM GMT are dispatched the same working day via tracked courier services, ensuring minimal time between order placement and receipt. Urgent research timelines are respected.

Batch-Specific Certificates of Analysis
Each vial is traceable to its production batch, with full HPLC chromatograms, mass spectrometry data, and purity verification documentation available. This supports institutional procurement requirements and audit compliance.

Cold-Chain Integrity
Temperature-controlled storage at 2°C–8°C prior to dispatch, with insulated packaging designed to maintain lyophilised product stability during transit. Long-term storage recommended at -20°C for extended stability.

Discreet & Secure Delivery
Plain, unbranded outer packaging protects your research privacy. All shipments are fully tracked with delivery confirmation.

Dedicated UK Support
Our UK-based technical support team is available to assist with product queries, storage guidance, and reconstitution protocols. No dosing, administration, or clinical guidance is provided—we support your research objectives exclusively.

Regulatory Compliance & In-Vitro Disclaimer

FOR IN-VITRO RESEARCH & LABORATORY USE ONLY

This product is a research-grade chemical supplied exclusively for:

• In-vitro laboratory experimentation

• Analytical testing and method development

• Biochemical assay and cellular model research

• Scientific study and educational purposes

STRICTLY NOT FOR:

• Human consumption, administration, or therapeutic application

• Veterinary use or animal experimentation outside licensed laboratory settings

• Diagnostic, treatment, or preventative medical purposes

• Any application outside a controlled laboratory environment

All users must comply with applicable UK and EU regulations governing the procurement, handling, and use of research chemicals. This product is not a medicinal product, dietary supplement, or foodstuff. No medical or therapeutic claims are made, expressed, or implied. Researchers are responsible for ensuring that their intended use complies with institutional ethics committees and relevant regulatory frameworks.