Description

Buy Glutathione 1,500mg (Reduced L-Glutathione) Online UK 

For laboratories and research institutions investigating oxidative stress, redox biology, and cellular detoxification pathways, our Glutathione 1,500mg delivers verified ≥98% HPLC purity with comprehensive analytical testing . This tripeptide (γ-L-Glutamyl-L-Cysteinyl-Glycine) is the most abundant intracellular thiol and the primary endogenous antioxidant buffer in mammalian cells . Manufactured under stringent controlled conditions, lyophilised to preserve molecular integrity, and preserved through our temperature-monitored cold-chain, every batch is accompanied by a comprehensive Certificate of Analysis. With 100% domestic UK stockholding and same-day dispatch on orders placed before 2:00 PM GMT, we eliminate customs delays that compromise research integrity.

Research Applications & Key Benefits

• Oxidative Stress & Redox Biology Research: Glutathione is the cell’s primary buffer against oxidative stress, directly scavenging reactive oxygen species (ROS) including superoxide anions, hydrogen peroxide, and hydroxyl radicals . Research applications include studying cellular responses to oxidative damage, redox homeostasis, and antioxidant defence mechanisms. Monitoring the GSH/GSSG ratio is a standard measure of cellular redox status—a low ratio indicates oxidative stress .

• Detoxification Pathway Modelling: Glutathione is a substrate for glutathione S-transferases (GSTs), catalysing the conjugation of GSH to xenobiotics for detoxification . Research examines Phase II detoxification pathways, heavy metal chelation (forming thiol conjugates with mercury, lead, and arsenic), and toxin interaction modelling .

• Mitochondrial Function Investigations: The mitochondrial glutathione pool protects the electron transport chain from oxidative damage . Mitochondrial GSH depletion leads to membrane permeability transition and apoptosis, making it critical for mitochondrial integrity research . Studies examine mitochondrial responses under redox modulation and glutathione’s role in mitochondrial bioenergetics.

• Glutathione Peroxidase & Enzyme Activity Studies: Glutathione serves as a cofactor for glutathione peroxidase enzymes, supporting research into enzymatic antioxidant systems, enzyme kinetics, and the role of selenium-dependent peroxidases in cellular protection .

• In-Vitro Cell Culture & Biochemical Assays: Suitable for controlled laboratory environments including cell culture supplementation (typically 1–10 mM cytoplasmic concentrations), enzymatic assays, and redox testing frameworks . GSH is essential for maintaining redox state and cell viability in many in vitro models .

• GST-Affinity Purification & Analytical Applications: Glutathione is crucial for glutathione S-transferase (GST) affinity purification and is used as a sensitive biomarker in oxidative stress and disease studies . The thiol (-SH) group is essential for redox balance investigations and antioxidant behaviour studies .

The Pure Peptides UK Advantage

100% Domestic UK Stockholding
All inventory is warehoused within the United Kingdom, eliminating international shipping delays, customs clearance uncertainties, and extended transit times. Your order ships from our UK facility directly to your laboratory .

Same-Day Dispatch Commitment
Orders confirmed before 2:00 PM GMT are dispatched the same working day via tracked courier services, ensuring minimal time between order placement and receipt .

Batch-Specific Certificates of Analysis
Each vial is traceable to its production batch, with full HPLC chromatograms and purity verification documentation available. Third-party testing confirms identity and purity standards .

Cold-Chain Integrity
Temperature-controlled storage at -20°C prior to dispatch, with insulated packaging designed to maintain lyophilised product stability during transit . As reduced glutathione oxidises readily, storage at -20°C in a dry, light-protected environment is recommended .

Discreet & Secure Delivery
Plain, unbranded outer packaging protects your research privacy. All shipments are fully tracked with delivery confirmation.

Dedicated UK Support
Our UK-based technical support team is available to assist with product queries, storage guidance, and reconstitution protocols. No dosing, administration, or clinical guidance is provided—we support your research objectives exclusively.

Regulatory Compliance & In-Vitro Disclaimer

FOR IN-VITRO RESEARCH & LABORATORY USE ONLY

This product is a research-grade chemical supplied exclusively for:

• In-vitro laboratory experimentation

• Analytical testing and method development

• Biochemical assay and cellular model research

• Scientific study and educational purposes 

STRICTLY NOT FOR:

• Human consumption, administration, or therapeutic application

• Veterinary use or animal experimentation outside licensed laboratory settings

• Diagnostic, treatment, or preventative medical purposes

• Any application outside a controlled laboratory environment 

All users must comply with applicable UK and EU regulations governing the procurement, handling, and use of research chemicals. This product is not a medicinal product, dietary supplement, or foodstuff. No medical or therapeutic claims are made, expressed, or implied. Researchers are responsible for ensuring that their intended use complies with institutional ethics committees and relevant regulatory frameworks.