CJC-1295 with DAC 2mg

Description

Buy CJC-1295 with DAC – 2 mg Online UK

For laboratories and research institutions investigating sustained growth hormone signaling dynamics, our CJC-1295 with DAC 2mg delivers verified ≥98% HPLC purity with full mass spectrometry confirmation. This synthetic 29-amino acid GHRH analogue incorporates a Drug Affinity Complex (DAC) moiety—a maleimidopropionic acid group that facilitates covalent binding to endogenous serum albumin, significantly extending the peptide’s effective half-life in vitro compared to non-DAC variants. Manufactured under stringent controlled conditions, vacuum-sealed in lyophilized form, and preserved through our temperature-monitored cold-chain, every batch is accompanied by a comprehensive Certificate of Analysis ensuring complete experimental traceability.

Research Applications & Key Benefits

• Sustained GHRH Receptor Signaling Studies: The DAC modification enables prolonged engagement with GHRH receptors in vitro, making this analogue a valuable molecular probe for investigating extended receptor activation dynamics, Gs/adenylate cyclase coupling, and cAMP/PKA signaling pathway modulation over extended time courses.

• Pulsatile vs. Continuous GH Secretion Modelling: Unlike non-DAC analogues, CJC-1295 with DAC demonstrates sustained bioactivity, allowing researchers to examine the physiological implications of prolonged GHRH receptor engagement on somatotroph biology, GH pulse dynamics, and feedback regulation.

• Metabolic & Endocrine Pathway Research: Investigated in studies examining growth hormone axis regulation, IGF-1 signalling, glucose metabolism, lipid oxidation, and body composition dynamics in preclinical models.

• Comparative Pharmacology: Provides an important experimental contrast to CJC-1295 without DAC, enabling researchers to evaluate the effects of prolonged half-life on signalling outcomes, receptor desensitisation, and downstream transcriptional regulation in controlled studies.

• Structural Stability & Bioactivity: The tetrasubstituted GRF backbone combined with the DAC conjugation confers enhanced in vitro stability while retaining full GHRH receptor bioactivity—confirmed through cell-based assays demonstrating sustained GH secretory activity.

The Pure Peptides UK Advantage

100% Domestic UK Stockholding
All inventory is warehoused within the United Kingdom, eliminating international shipping delays, customs clearance uncertainties, and extended transit times that compromise peptide stability.

Same-Day Dispatch Commitment
Orders confirmed before 2:00 PM GMT are dispatched the same working day via tracked courier services, ensuring minimal time between order placement and receipt.

Batch-Specific Certificates of Analysis
Each vial is traceable to its production batch, with full HPLC chromatograms, mass spectrometry data, and purity verification documentation available—supporting institutional procurement requirements and audit compliance.

Cold-Chain Integrity
Temperature-controlled storage at 2°C–8°C prior to dispatch, with insulated packaging designed to maintain lyophilised product stability during transit. Long-term storage recommended at -20°C for extended stability .

Discreet & Secure Delivery
Plain, unbranded outer packaging protects your research privacy. All shipments are fully tracked with delivery confirmation.

Dedicated UK Support
Our UK-based technical support team is available to assist with product queries, storage guidance, and reconstitution protocols. No dosing, administration, or clinical guidance is provided—we support your research objectives exclusively.

Regulatory Compliance & In-Vitro Disclaimer

FOR IN-VITRO RESEARCH & LABORATORY USE ONLY

This product is a research-grade chemical supplied exclusively for:

• In-vitro laboratory experimentation

• Analytical testing and method development

• Biochemical assay and cellular model research

• Scientific study and educational purposes 

STRICTLY NOT FOR:

• Human consumption, administration, or therapeutic application

• Veterinary use or animal experimentation outside licensed laboratory settings

• Diagnostic, treatment, or preventative medical purposes

• Any application outside a controlled laboratory environment 

All users must comply with applicable UK and EU regulations governing the procurement, handling, and use of research chemicals. This product is not a medicinal product, dietary supplement, or foodstuff. No medical or therapeutic claims are made, expressed, or implied. Researchers are responsible for ensuring that their intended use complies with institutional ethics committees and relevant regulatory frameworks .