Epitalon 10mg

Description

Buy Epitalon – 10 mg Online UK

For laboratories and research institutions investigating telomere biology, cellular senescence, and neuroendocrine regulation, our Epitalon 10mg delivers verified ≥98% HPLC purity with full mass spectrometry confirmation. This synthetic tetrapeptide (Ala-Glu-Asp-Gly) corresponds to the active fragment of the pineal gland bioregulator Epithalamin and has become a compound of significant interest in gerontological, epigenetic, and biochemical research. Manufactured under stringent controlled conditions using solid-phase peptide synthesis (SPPS), vacuum-sealed in lyophilized form, and preserved through our temperature-monitored cold-chain, every batch is accompanied by a comprehensive Certificate of Analysis. With 100% domestic UK stockholding and same-day dispatch on orders placed before 2:00 PM GMT, we eliminate customs delays and temperature excursions that compromise research integrity .

Research Applications & Key Benefits

• Telomere Biology & Telomerase Regulation: Epitalon has been investigated in human cell line studies for its ability to extend telomere length through the upregulation of hTERT mRNA expression and telomerase enzyme activity . Research has demonstrated dose-dependent telomere elongation in normal epithelial and fibroblast cells, making it a valuable tool for studying telomere dynamics and cellular ageing mechanisms .

• Geroprotective & Longevity Research: Studies in model organisms have investigated Epitalon’s geroprotective properties, with evidence of lifespan extension in Drosophila melanogaster at concentrations significantly lower (16,000 to 80,000,000 times lower) than those required for melatonin . The compound exhibits antioxidant properties that, in some assays, exceed those of melatonin while also stimulating endogenous antioxidant enzymes including superoxide dismutase (SOD) and ceruloplasmin .

• Cellular Senescence & Wound Healing Models: In vitro studies have examined Epitalon’s effects on cellular regeneration and wound healing. Research using hyperglycaemia-injured ARPE-19 cells demonstrated that Epitalon restored impaired wound healing by inhibiting hyperglycaemia-induced epithelial-mesenchymal transition (EMT) and fibrosis .

• Neuroendocrine & Pineal Signalling: Epitalon is studied in models of pineal gland function, melatonin synthesis, and circadian rhythm regulation. Research has investigated its effects on neuron activity in the rat neocortex, with evidence of multiphasic neuronal responses .

• Epigenetic & Gene Expression Studies: Investigations into the epigenetic mechanisms of AEDG peptide (Epitalon) have examined its influence on neurogenic differentiation gene expression and protein synthesis in human mesenchymal stem cells .

The Pure Peptides UK Advantage

100% Domestic UK Stockholding
All inventory is warehoused within the United Kingdom, eliminating international shipping delays, customs clearance uncertainties, and extended transit times. Your order ships from our UK facility directly to your laboratory.

Same-Day Dispatch Commitment
Orders confirmed before 2:00 PM GMT are dispatched the same working day via tracked courier services (Royal Mail 24hr Tracked), ensuring minimal time between order placement and receipt .

Batch-Specific Certificates of Analysis
Each vial is traceable to its production batch, with full HPLC chromatograms, mass spectrometry data, and purity verification documentation available. Independent third-party testing confirms identity and purity standards .

Cold-Chain Integrity
Temperature-controlled storage at 2°C–8°C prior to dispatch, with insulated packaging designed to maintain lyophilised product stability during transit. Long-term storage recommended at -20°C, protected from light and moisture .

Discreet & Secure Delivery
Plain, unbranded outer packaging protects your research privacy. All shipments are fully tracked with delivery confirmation. No compound names appear on external packaging.

Dedicated UK Support
Our UK-based technical support team is available to assist with product queries, storage guidance, and reconstitution protocols. No dosing, administration, or clinical guidance is provided—we support your research objectives exclusively.

Regulatory Compliance & In-Vitro Disclaimer

FOR IN-VITRO RESEARCH & LABORATORY USE ONLY

This product is a research-grade chemical supplied exclusively for:

• In-vitro laboratory experimentation

• Analytical testing and method development

• Biochemical assay and cellular model research

• Scientific study and educational purposes

STRICTLY NOT FOR:

• Human consumption, administration, or therapeutic application

• Veterinary use or animal experimentation outside licensed laboratory settings

• Diagnostic, treatment, or preventative medical purposes

• Any application outside a controlled laboratory environment

All users must comply with applicable UK and EU regulations governing the procurement, handling, and use of research chemicals. This product is not a medicinal product, dietary supplement, or foodstuff. No medical or therapeutic claims are made, expressed, or implied. Researchers are responsible for ensuring that their intended use complies with institutional ethics committees and relevant regulatory frameworks .